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| Abbreviations and Acronyms | |
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| Synopsis and Highlights | |
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| Introduction | |
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| The Learning Health System | |
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| The Digital Health Infrastructure | |
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| About the Digital Infrastructure Meetings | |
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| Visioning Perspectives on the Digital Health Utility | |
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| Introduction | |
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| Informed and Empowered Patients: Moving Beyond a Bystander in Care | |
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| Building a Learning Health System Clinicians Will Use | |
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| Improving Quality and Safety | |
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| Clinical Research in the Information Age | |
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| Integrating the Public Health Perspective | |
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| Technical Issues for the Digital Health Infrastructure | |
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| Introduction | |
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| Building a Standards and Interoperability Framework | |
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| Interoperability for the Learning Health System | |
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| Promoting Secure Data Liquidity | |
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| Innovative Approaches to Information Diversity | |
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| Engaging Patient and Population Needs | |
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| Introduction | |
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| Electronic Health Data for High-Value Health Care | |
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| Engaging Individuals in Population Health Monitoring | |
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| Optimizing Chronic Disease Care and Control | |
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| Targeting Population Health Disparities | |
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| Weaving a Strong Trust Fabric | |
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| Introduction | |
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| Demonstrating Value to Secure Trust | |
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| Policies and Practices to Build Public Trust | |
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| HDPAA and a Learning Healthcare System | |
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| Building a Secure Learning Health System | |
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| Stewardship and Governance in the Learning Health System | |
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| Introduction | |
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| Governance Coordination, Needs, and Options | |
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| Consistency and Reliability in Reporting for Regulators | |
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| Complying with Patient Expectations for Data De-Identification | |
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| Information Governance in the National Health Service (UK) | |
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| Perspectives on Innovation | |
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| Introduction | |
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| Conceptualizing a U.S. Population Health Record | |
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| Accelerating Innovation Outside the Private Sector | |
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| Combinatorial Innovation in Health Information Technology | |
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| Fostering the Global Dimension of the Health Data Trust | |
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| Introduction | |
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| TRANSFoRm: Translational Medicine and Patient Safety ; in Europe | |
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| Healthgrids, the SHARE Project, and Beyond | |
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| A Global Perspective on the Importance of Systematic Data to Drive Improvements in Care | |
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| Informatics and the Future of Infectious Disease Surveillance | |
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| Growing the Digital Health Infrastructure | |
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| Introduction | |
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| Technical Progress | |
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| Knowledge Generation and Use | |
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| Patient and Population Engagement | |
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| Governance | |
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| Common Themes and Principles | |
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| Accelerating Progress | |
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| Introduction | |
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| Stakeholder Engagement | |
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| Technical Progress | |
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| Infrastructure Use | |
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| Governance | |
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| Opportunities in the Next Stages of Meaningful Use | |
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| Stakeholder Responsibilities and Opportunities | |
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| Appendixes | |
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| The Learning Health System and the Digital Health Utility | |
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| Case Studies for the Digital Health Infrastructure | |
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| Example Stakeholder Responsibilities and Opportunities | |
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| Summary Overview of Meaningful Use Objectives | |
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| PCAST Report Recommendations | |
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| Workshop Agendas | |
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| Workshop Participants | |