"This book explores the role of Metallothioneins (MTs) in the field of neurological disorders (brain inflammation, Alzheimer's and prion diseases, autism, ALS, etc.), cardiology (cardiomyopathy, atherosclerosis), and oncology (melanoma, prostate and breast cancer), through authoritative contributions and a description of basic biochemical information and paradigmatic pathological events."--BOOK JACKET.
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| List of Contributors | |
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| Metallothionein in Neurological Disorders | |
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| Metallothionein Structure and Reactivity | |
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| Thiol Reactivity as a Central Aspect of Metallothionein's Mechanism of Action | |
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| Metallothioneins and Neurodegenerative Diseases | |
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| Metallothionein and Brain Inflammation | |
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| Metallothionein and Autism | |
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| The Role of Metallothionein and Astrocyte-Neuron Interactions in Injury to the CNS | |
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| Metallothionein in Oncology | |
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| Metallothioneins and Oncology | |
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| Metallothionein and Melanoma | |
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| Metallothionein and Breast Cancer | |
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| Metallothioneins and Prostate Cancer | |
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| Metallothionein and Colorectal Tumors | |
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| Metallothionein in Cardiopathy | |
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| Metallothionein and Cardiomyopathy | |
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| Zinc Status, Metallothioneins and Atherosclerosis in the Elderly | |
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| Metallothionein in Hepatology | |
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| Metallothioneins and Liver Diseases | |
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| Index | |
Danilo Milardi obtained a degree in Industrial Chemistry from the University of Catania before going on to obtain a PhD in protein thermodynamics. He has been involved in various MIUR projects concerned with protein thermodynamics and in 1997 obtained a fellowship of the University of Catania in collaboration with Cyanamid S.p.A. He currently works as research scientist at the Italian Consiglio Nazionale delle Ricerche (CNR) - Instituto di Biostrutture e Bioimmagini. He also has extensive experience in teaching and the coordination of research projects. Dr Milardi was a member of the organizing committee of the 8th National Meeting of the Italian Liquid Crystal Society and is the author of 41 scholarly papers and 60 communications to national and international congresses. Enrico Rizzarelli is currently a professor in the Dipartimento di Scienze Chimiche at the Università di Catania. His main research Interests include: molecular recognition processes assisted by metal ions; synthesis, characterization and biological activity of copper(II) coordination compounds; protein misfolding diseases and metal ions, and model systems of metal enzymes with antioxidant activities. He is a member of numerous scholarly societies and has been an invited speaker or chair at many national and international meetings. He regularly referees manuscripts for numerous international journals and has authored about 220 papers himself. He has co-authored and guest edited several key books and been the author of three European patents. Enrico Rizzarelli also refereed research projects on the behalf of Italian and international research bodies.
